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Mortality in Patients with Basal and Squamous Cell Carcinoma
There are varying reports of the association of basal cell carcinoma and cutaneous squamous cell carcinoma with mortality. A recent review looked at the all-cause mortality of the general population after a diagnosis of basal cell carcinoma or squamous cell carcinoma.
The systematic review and meta analysis – recently published in the Journal of the American Academy of Dermatology – encompassed 464,230 patients with basal cell carcinoma and 175,849 with squamous cell carcinoma.
It yielded summary relative mortalities of 0.92 in basal cell carcinoma and 1.25 in squamous cell carcinoma. That is, all studies showed a statistically significant increased relative mortality in patients with squamous cell carcinoma.
Therefore, the review found that patients with squamous cell carcinoma are at higher risk for death from any cause compared with the general population.
Wehner, M.R. et al. (April 2018.) All-cause mortality in patients with basal and squamous cell carcinoma: A systematic review and meta-analysis. Journal of the American Academy of Dermatology. Volume 78, Issue 4, Pages 663–672.e3. DOI: https://doi.org/10.1016/j.jaad.2017.11.026
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