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In the blog category “Case Studies” Professor David Wilkinson offers an excellent platform to discuss clinical problems and cases within a closed alumni community. This area is password-protected and only accessible to past HealthCert Certificate course participants.

We encourage you to submit clinical images and questions so we can all learn together.

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Mortality in Patients with Basal and Squamous Cell Carcinoma


There are varying reports of the association of basal cell carcinoma and cutaneous squamous cell carcinoma with mortality. A recent review looked at the all-cause mortality of the general population after a diagnosis of basal cell carcinoma or squamous cell carcinoma.

Case discussion: How would you treat this patient? [23 April]

Case discussion

This week we have another interesting case. This lesion was on the arm and the patient was unaware of it. What is your assessment of the clinical and dermoscopic images, and what would you do next? 

Most Effective Treatment for Superficial Basal Cell Carcinoma

superficial basal cell carcinoma

A variety of non-invasive treatments are available in the treatment of superficial basal cell carcinoma. A study looked at three different methods to determine the most effective approach after one, three and five years: photodynamic therapy, topical imiquimod or topical 5-fluorouracil.

Case discussion: How would you treat this patient? [16 April]

Case discussion

This week we have an interesting case from Dr Nameer Wadea. An 34-year-old male, uses sun bed frequently and had developed two small lesions on the left side of the face – injures them when he shaves. Dr Wadea asks “your opinion regarding liquid nitrogen vs excisional biopsy – as cosmetic concern is important” Please review […]

Can a course of fluorouracil cream reduce a person’s risk of BCC and SCC?


This month’s paper from JAMA Dermatology, by Weinstock et al, is instructive. The authors did a randomised trial of five per cent fluorouracil cream applied to the face, to see if a two to four week application would reduce the number of basal cell carcinomas (BCC) and squamous cell carcinomas (SCC) in the following year.

Skin Cancer Update with Prof Giuseppe Argenziano [April 2018]

skin cancer update APR18

In this month’s skin cancer update, Professor Giuseppe Argenziano discusses melanoma that arise within pre-existing congenital naevi. The risk of melanoma arising out of large congenital naevi in a person’s lifetime is 1 in 10. The risk in intermediate congenital naevi is 1 in 200 and the risk in small congenital naevi is 1 in […]

How can computer vision aid in melanoma detection?

computer vision

How can computer vision aid in melanoma detection? A study recently published in the Journal of the American Academy of Dermatology compared the diagnostic accuracy of computer algorithms to dermatologists using dermoscopic images. The study involved 100 randomly selected dermoscopic images comprising of 50 melanomas, 44 naevi, and six lentigines. Researchers used both non-learned and machine learning […]

Case discussion: How would you treat this patient? [26 March]

Case discussion

This week we have an interesting case from Dr Colin Armstrong. An elderly gentleman presented for a skin check, and a very obvious dark lesion on the lower back was noted. Please review and describe the clinical and dermoscopic image. What is your evaluation, and proposed next step/s?

Gefitinib for Incurable, Recurrent or Metastatic Squamous Cell Carcinoma


A recent study looked at the efficacy of gefitinib in patients with cutaneous squamous cell carcinoma (SCC) whose cancer was not amenable to curative therapy including surgery or radiation. The epidermal growth factor receptor plays a key role in the carcinogenesis of SCC. However, there are limited data on the efficacy of epidermal growth factor […]

Case discussion: How would you treat this patient? [19 March]

This week we have an engaging case from Dr Dorothy Dowd. A mid thirties gentleman obviously has multiple mole syndrome from the image below. So, two issues: What is your assessment of the 2 lesions Dr Dowd shows here? How do you manage these patients in your practice?


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